Compile Data Set for Download or QSAR
Found 59 Enz. Inhib. hit(s) with all data for entry = 50011569
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108176(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18510(5-{3-[(2,4-diaminopyrimidin-5-yl)methyl]-4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18510(5-{3-[(2,4-diaminopyrimidin-5-yl)methyl]-4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18510(5-{3-[(2,4-diaminopyrimidin-5-yl)methyl]-4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108180(8-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108172(6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108179(9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50058401(2,4-Diamino-5-[4-chloro-3-[3-[2-(acetyloxy)ethyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108176(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108174(7-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108174(7-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108176(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108181(5-(2-Methoxy-5-pentyloxy-benzyl)-pyrimidine-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108180(8-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108178(5-(5-Hexyloxy-2-methoxy-benzyl)-pyrimidine-2,4-dia...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108179(9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108172(6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50063984(5-((naphthalen-1-ylthio)methyl)furo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108172(6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108173(5-(5-Heptyloxy-2-methoxy-benzyl)-pyrimidine-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50058399(5-[4-Chloro-3-(morpholin-4-ylazo)-phenyl]-6-ethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18506(6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108174(7-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108176(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029763(5-(3,5-Diethoxy-4-pyrrol-1-yl-benzyl)-pyrimidine-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108175(5-(2-Methoxy-5-octyloxy-benzyl)-pyrimidine-2,4-dia...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18510(5-{3-[(2,4-diaminopyrimidin-5-yl)methyl]-4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108179(9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108173(5-(5-Heptyloxy-2-methoxy-benzyl)-pyrimidine-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108173(5-(5-Heptyloxy-2-methoxy-benzyl)-pyrimidine-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108181(5-(2-Methoxy-5-pentyloxy-benzyl)-pyrimidine-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108180(8-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50063990(5-((biphenyl-2-ylamino)methyl)furo[2,3-d]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108178(5-(5-Hexyloxy-2-methoxy-benzyl)-pyrimidine-2,4-dia...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50050396(6-(Naphthalen-1-ylsulfanylmethyl)-pteridine-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108173(5-(5-Heptyloxy-2-methoxy-benzyl)-pyrimidine-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108174(7-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108179(9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108180(8-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108178(5-(5-Hexyloxy-2-methoxy-benzyl)-pyrimidine-2,4-dia...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108175(5-(2-Methoxy-5-octyloxy-benzyl)-pyrimidine-2,4-dia...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108172(6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108181(5-(2-Methoxy-5-pentyloxy-benzyl)-pyrimidine-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50059929(8-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine | 8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CJ2PubMed
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