Compile Data Set for Download or QSAR
Found 31 Enz. Inhib. hit(s) with all data for entry = 50015338
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50098378((1-Hydroxy-1-phosphono-2-pyridin-2-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585603(CHEMBL5087030)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585613(CHEMBL5088349)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM544004(US11279719, Example I-36)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520641(CHEMBL4455060 | US11279719, Example I-13)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585614(CHEMBL5082193)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585601(CHEMBL5077349)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585611(CHEMBL5077117)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585612(CHEMBL5089506)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585604(CHEMBL5083916)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585608(CHEMBL5075557)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585606(CHEMBL5085126)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585605(CHEMBL5080782)copy SMILES
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520640(CHEMBL4472025 | US11279719, Example I-34)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520637(CHEMBL4577077 | US11279719, Example I-37)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585599(CHEMBL5088555)copy SMILES
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585602(CHEMBL5075029)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585607(CHEMBL5080121)copy SMILES
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585600(CHEMBL5092247)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520645(CHEMBL2347859 | US11279719, Example C-5)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585609(CHEMBL5082291)copy SMILES
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585610(CHEMBL5081807)copy SMILES
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520639(CHEMBL4465832 | US11279719, Example I-6)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM543975(US11279719, Example I-7)copy SMILES
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM544003(US11279719, Example I-35)copy SMILES
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM544000(US11279719, Example I-32)copy SMILES
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585613(CHEMBL5088349)copy SMILES
Affinity DataIC50: 460nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520645(CHEMBL2347859 | US11279719, Example C-5)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585614(CHEMBL5082193)copy SMILES
Affinity DataIC50: 730nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520637(CHEMBL4577077 | US11279719, Example I-37)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520639(CHEMBL4465832 | US11279719, Example I-6)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed