Compile Data Set for Download or QSAR
Found 26 Enz. Inhib. hit(s) with all data for entry = 50017199
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178971((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178971((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178972(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178970(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethylquino...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178972(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178976(5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178970(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethylquino...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50241363(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178976(5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50241363(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50241362(5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50241362(5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178971((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...)copy SMILEScopy InChI
Affinity DataEC50:  1.30nMAssay Description:Efficacy against TRAF-alpha-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)copy SMILEScopy InChI
Affinity DataEC50:  4.70nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178971((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...)copy SMILEScopy InChI
Affinity DataEC50:  3.5nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Efficacy against TRAF-alpha-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178972(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...)copy SMILEScopy InChI
Affinity DataEC50:  4.10nMAssay Description:Efficacy against TRAF-alpha-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178972(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...)copy SMILEScopy InChI
Affinity DataEC50:  4.30nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Efficacy against TRAF-alpha-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178970(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethylquino...)copy SMILEScopy InChI
Affinity DataEC50:  83nMAssay Description:Efficacy against TRAF-alpha-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178970(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethylquino...)copy SMILEScopy InChI
Affinity DataEC50:  49nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataEC50:  4.20nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed