Compile Data Set for Download or QSAR
Found 81 Enz. Inhib. hit(s) with all data for entry = 50017353
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50515430(NETARSUDIL | US11608319, Compound AR-13324)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50515430(NETARSUDIL | US11608319, Compound AR-13324)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50601415(AR-12286 | AR-12286 FREE BASE | Ar-12286 | VEROSUD...)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50601415(AR-12286 | AR-12286 FREE BASE | Ar-12286 | VEROSUD...)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataKi:  4.40nMMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50601416(CHEMBL5182402)copy SMILES
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)copy SMILEScopy InChI
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50417857(CHEMBL1667969)copy SMILEScopy InChI
Affinity DataKi:  36nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)copy SMILEScopy InChI
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50087135(CHEMBL3426621)copy SMILEScopy InChI
Affinity DataKi:  330nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM188514(4,7,7-trimethyl-4-phenyl-3-(trifluoromethyl)-2,4,6...)copy SMILES
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50124208(ASP-015K | ASP015K | Peficitinib)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50601417(CHEMBL5178166)copy SMILES
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50519662(CHEMBL4438748)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM50124208(ASP-015K | ASP015K | Peficitinib)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM50124208(ASP-015K | ASP015K | Peficitinib)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50124208(ASP-015K | ASP015K | Peficitinib)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
LigandPNGBDBM50505940(CHEMBL4449840)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM27344(2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))TBA
LigandPNGBDBM319585(US10174007, Example 4 | US10787438, Example 4 | US...)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM402040(Preparation of N-(3-(5-chloro-2-(4-fluoro-3-(N-met...)copy SMILEScopy InChI
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))TBA
LigandPNGBDBM50443871(CHEMBL3091536)copy SMILEScopy InChI
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50087135(CHEMBL3426621)copy SMILEScopy InChI
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
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