Compile Data Set for Download or QSAR
Found 71 Enz. Inhib. hit(s) with all data for entry = 50018224
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50407243(CHEMBL5275998)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase(Homo sapiens)TBA
LigandPNGBDBM50407246(CHEMBL5279916)copy SMILEScopy InChI
Affinity DataKi:  530nMAssay Description:Negative log concentration of antagonistic compound was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelinase C(Bacillus cereus)TBA
LigandPNGBDBM248063(SMY-540)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCeramide synthase 2(Homo sapiens)TBA
LigandPNGBDBM50158336(2-(4-octylphenethyl)-2-aminopropane-1,3-diol | 2-A...)copy SMILEScopy InChI
Affinity DataKi:  2.15E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelinase C(Bacillus cereus)TBA
LigandPNGBDBM248061(SMY-471)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingomyelinase C(Bacillus cereus)TBA
LigandPNGBDBM248057(RY221B-a)copy SMILEScopy InChI
Affinity DataKi:  5.20E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingomyelin phosphodiesterase 3(Homo sapiens)TBA
LigandPNGBDBM29040(cambinol)copy SMILEScopy InChI
Affinity DataKi:  7.00E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingosine kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)copy SMILEScopy InChI
Affinity DataKi:  7.90E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Rattus norvegicus)TBA
LigandPNGBDBM50092055((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)copy SMILEScopy InChI
Affinity DataKi:  8.28E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingosine kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50576(2-(4,5-dihydroxy-2-methyl-phenyl)-6-hydroxy-4-meth...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523252((1r,4r)-4-(4- chlorophenyl)- N-(5-hydroxy- pyridin...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523251(N-(5-hydroxy- pyridin-2-yl)-7- methyloctan- amide ...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523243(N-(5-hydroxy- pyridin-2-yl)- 4-cyclohexyl- benzami...)copy SMILES
Affinity DataIC50: 4nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Rattus norvegicus)TBA
LigandPNGBDBM50407243(CHEMBL5275998)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50407243(CHEMBL5275998)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523241(N-(4-hydroxy- phenyl)-4- cyclohexyl- benzamide | U...)copy SMILES
Affinity DataIC50: 90nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50092055((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50407244(CHEMBL5268107)copy SMILEScopy InChI
Affinity DataIC50: 155nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50407385(CHEMBL5284450)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetCeramide synthase 1(Mus musculus)TBA
LigandPNGBDBM50407245(CHEMBL5268405)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 3(Homo sapiens)TBA
LigandPNGBDBM50407388(CHEMBL5267817)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 3(Homo sapiens)TBA
LigandPNGBDBM50407390(CHEMBL5279596)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetCeramide synthase 1(Homo sapiens)TBA
LigandPNGBDBM50407245(CHEMBL5268405)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelinase C(Bacillus cereus)TBA
LigandPNGBDBM248063(SMY-540)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Mus musculus)TBA
LigandPNGBDBM50407382(CHEMBL5280187)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Mus musculus)TBA
LigandPNGBDBM50407379(CHEMBL5276486)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelinase C(Bacillus cereus)TBA
LigandPNGBDBM248061(SMY-471)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50407378(CHEMBL1514251)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50407383(CHEMBL5278618)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase(Homo sapiens)TBA
LigandPNGBDBM50407347(CHEMBL5273649)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+3nMAssay Description:Antagonistic activity on 5-hydroxytryptamine 2B receptor of Rat stomach fundus;ND is not determinedMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelinase C(Bacillus cereus)TBA
LigandPNGBDBM248057(RY221B-a)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Rattus norvegicus)TBA
LigandPNGBDBM50407241(CHEMBL5290345)copy SMILEScopy InChI
Affinity DataIC50: 1.68E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50407390(CHEMBL5279596)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase(Homo sapiens)TBA
LigandPNGBDBM50407249(CHEMBL5273927)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50407376(CHEMBL5284579)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50128902(CHEMBL59342 | Pyridin-4-ylmethyl-carbamic acid (E)...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase(Homo sapiens)TBA
LigandPNGBDBM50407248(CHEMBL5271590)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase(Homo sapiens)TBA
LigandPNGBDBM50407247(CHEMBL5276301)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Rattus norvegicus)TBA
LigandPNGBDBM50092055((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 2.32E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Mus musculus)TBA
LigandPNGBDBM50407381(CHEMBL5285219)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Mus musculus)TBA
LigandPNGBDBM50407380(CHEMBL5279211)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50128891(CHEMBL261976 | Pyridin-4-ylmethyl-carbamic acid (E...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50407377(CHEMBL5270975)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50407375(CHEMBL5285849)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50407373(CHEMBL2365779)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 3(Rattus norvegicus)TBA
LigandPNGBDBM29040(cambinol)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetCeramide synthase 2(Homo sapiens)TBA
LigandPNGBDBM50158336(2-(4-octylphenethyl)-2-aminopropane-1,3-diol | 2-A...)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
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