Compile Data Set for Download or QSAR
Found 128 Enz. Inhib. hit(s) with all data for entry = 50031497
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314225((R)-4-acetamido-2-(biphenyl-4-ylsulfonamido)-N-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314221((R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoin...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314221((R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoin...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314221((R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoin...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50294120(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of ADAM17 in human SKOV3 cells assessed as inhibition of EGF-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314221((R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoin...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of ADAM17 in human SKOV3 cells assessed as inhibition of EGF-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314228((R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfona...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314225((R)-4-acetamido-2-(biphenyl-4-ylsulfonamido)-N-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of ADAM17 in human A2774 cells assessed as inhibition of pervanadate-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(CHEMBL561625 | N-hydroxy-2-(N-isobutylbiphenyl-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314224((R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonami...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of ADAM17 in human A2774 cells assessed as inhibition of pervanadate-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314228((R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfona...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314224((R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonami...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314228((R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfona...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314224((R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonami...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM11328(CHEMBL83508 | Hydroxamate 9 | N-hydroxy-2-[(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50294120(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314225((R)-4-acetamido-2-(biphenyl-4-ylsulfonamido)-N-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(CHEMBL561625 | N-hydroxy-2-(N-isobutylbiphenyl-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314226(2-(4-bromophenylsulfonamido)-N-hydroxyacetamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of ADAM17 in human MCF7 cells assessed as inhibition of pervanadate-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of ADAM17 in human MCF7 cells assessed as inhibition of pervanadate-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314228((R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfona...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314224((R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonami...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50294120(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of ADAM17 in human GI-CA-N cells assessed as inhibition of pervanadate-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of ADAM17 in human GI-CA-N cells assessed as inhibition of constitutive sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314223((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of ADAM17 in human GI-CA-N cells assessed as inhibition of constitutive sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of ADAM17 in human SKOV3 cells assessed as inhibition of EGF-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of ADAM17 in human MDA-MB-468 cells assessed as inhibition of EGF-induced sALCAM release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM11328(CHEMBL83508 | Hydroxamate 9 | N-hydroxy-2-[(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
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