Compile Data Set for Download or QSAR
Found 32 Enz. Inhib. hit(s) with all data for entry = 50038387
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair