Found 39 Enz. Inhib. hit(s) with all data for entry = 50040568 TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKi: 1.67E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKi: 1.87E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKi: 2.15E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKi: 5.00E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKi: 8.00E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of STAT3 assessed as suppression of STAT3-DNA interaction by EMSAMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction by AlphaScreen assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of STAT3 expressed in human HCT116 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of STAT3 SH2 domain using 5-carboxyfluorescein-GY(PO3H2)LPQTV-NH2 as substrate preincubated for 60 mins prior to substrate addition by flu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of STAT1 SH2 domain assessed as inhibition of STAT1 SH2-phosphotyrosine interaction by AlphaScreen assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of STAT3 dimerization in EGF-stimulated mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction aft...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 1.44E+5nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 2.56E+5nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1(Mus musculus)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of STAT1 dimerization in EGF-stimulated mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT1-DNA interaction aft...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 4.47E+5nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of STAT3 expressed in human U3A cells after 1 hr by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 2.74E+3nMAssay Description:Binding affinity to STAT3 SH2 in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFRMore data for this Ligand-Target Pair
