Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant Btk after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Irreversible inhibition of EGFRMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Btk in human Ramos cellsMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of RSK2 transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of EGF-induced autophosphorylation of EGFR in human A431 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged EGFR expressed in sf9 cells by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant FGFR1More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of RSK2 transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of GST-tagged Plk1 using recombinant protein X as a substrate containing threonine residuesMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of GST-tagged ErbB2 expressed in sf9 cells by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of GST-tagged ErbB4 expressed in sf9 cells by ELISAMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 149nMAssay Description:Inhibition of human AKT1 using biotinylated GSKalpha peptide (SGRARTSSFA) as a substrate after 1 hrMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 313nMAssay Description:Inhibition of human AKT1 using biotinylated GSKalpha peptide (SGRARTSSFA) as a substrate after 1 hrMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of MKK4More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of chicken c-Src using IYGEFKKK peptide as a substrate and [32P]ATP by fluorescence analysisMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of chicken c-SrcMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of chicken c-SrcMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of chicken c-SrcMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of chicken c-SrcMore data for this Ligand-Target Pair
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