Compile Data Set for Download or QSAR
Found 35 Enz. Inhib. hit(s) with all data for entry = 50043935
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448558(CHEMBL3127349)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448559(CHEMBL3127352)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447292(CHEMBL3113979)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448562(CHEMBL3127348)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448563(CHEMBL3127347)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448561(CHEMBL3127350)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448560(CHEMBL3127351)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448571(CHEMBL3127361)copy SMILEScopy InChI
Affinity DataIC50: 215nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448578(CHEMBL3127354)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448572(CHEMBL3127360)copy SMILEScopy InChI
Affinity DataIC50: 701nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448569(CHEMBL3127341)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448567(CHEMBL3127343)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448568(CHEMBL3127342)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448575(CHEMBL3127357)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448564(CHEMBL3127346)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448565(CHEMBL3127345)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448570(CHEMBL3127340)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448573(CHEMBL3127359)copy SMILEScopy InChI
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448577(CHEMBL3127355)copy SMILEScopy InChI
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448576(CHEMBL3127356)copy SMILEScopy InChI
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448566(CHEMBL3127344)copy SMILEScopy InChI
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448574(CHEMBL3127358)copy SMILEScopy InChI
Affinity DataIC50: 5.34E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448579(CHEMBL3127353)copy SMILEScopy InChI
Affinity DataIC50: 9.15E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448560(CHEMBL3127351)copy SMILEScopy InChI
Affinity DataEC50:  4.76E+3nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)copy SMILEScopy InChI
Affinity DataEC50:  3.64E+3nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448563(CHEMBL3127347)copy SMILEScopy InChI
Affinity DataEC50:  5.47E+3nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448562(CHEMBL3127348)copy SMILEScopy InChI
Affinity DataEC50:  3.99E+3nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448559(CHEMBL3127352)copy SMILEScopy InChI
Affinity DataEC50:  220nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)copy SMILEScopy InChI
Affinity DataKd:  240nMAssay Description:Binding affinity to GKRP (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of human glucokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetHexokinase-4(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447292(CHEMBL3113979)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of human glucokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448561(CHEMBL3127350)copy SMILEScopy InChI
Affinity DataEC50:  890nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50448558(CHEMBL3127349)copy SMILEScopy InChI
Affinity DataEC50:  1.81E+3nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447292(CHEMBL3113979)copy SMILEScopy InChI
Affinity DataEC50:  82nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair