Compile Data Set for Download or QSAR
Found 31 Enz. Inhib. hit(s) with all data for entry = 50045945
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50088504(A-84538 | ABBOTT-84538 | CHEBI:45409 | Norvir | Ri...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50088504(A-84538 | ABBOTT-84538 | CHEBI:45409 | Norvir | Ri...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-Dihydroxyanthraquinone | 2,6-dihydroxy-9,10-an...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-Dihydroxyanthraquinone | 2,6-dihydroxy-9,10-an...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23420(7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM25759(CHEMBL723 | Carvedilol | Coreg | Dilatrend | Eucar...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50187243(17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM25759(CHEMBL723 | Carvedilol | Coreg | Dilatrend | Eucar...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM11021((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol |...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50187243(17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM11021((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol |...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 4-methylumbelliferone...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 4-methylumbelliferone...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50088507(CHEBI:63804 | CHEMBL1908021)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23420(7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50088507(CHEBI:63804 | CHEMBL1908021)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM30705(CHEMBL744 | MLS000069369 | RILUZOLE | SMR000058231...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM30705(CHEMBL744 | MLS000069369 | RILUZOLE | SMR000058231...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23450(1-Naphthalenol | 1-Naphthol | CHEMBL122617 | Napht...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23450(1-Naphthalenol | 1-Naphthol | CHEMBL122617 | Napht...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50418088(7-ETHYL-10-HYDROXY-CAMPTOTHECIN)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC343RPubMed