Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for entry = 50047838
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM239101(US10195181, Example 2.2 | US9403810, 2.2)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S2BPubMed
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50193010(CHEMBL3949800)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S2BPubMed
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM239094(US10195181, Example 1.3 | US9403810, 1.3)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S2BPubMed
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50193011(CHEMBL3945602)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S2BPubMed
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM239105(US10195181, Example 6 | US9403810, 6)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S2BPubMed
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM239114(US9403810, 14)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S2BPubMed