Compile Data Set for Download or QSAR
Found 30 Enz. Inhib. hit(s) with all data for entry = 50048294
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212247(CHEMBL3982065)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212246(CHEMBL3953547)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212246(CHEMBL3953547)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212246(CHEMBL3953547)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212246(CHEMBL3953547)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212246(CHEMBL3953547)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+5nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+5nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed