Found 65 Enz. Inhib. hit(s) with all data for entry = 6572 TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 0.180nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 0.190nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 0.320nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 0.550nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 0.570nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 0.700nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.70nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 2.21nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 3.64nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 4.01nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 4.66nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 7.40nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 8nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 15.6nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 24.3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 37.3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 39.5nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 62.2nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 87.5nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 143nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 150nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 184nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 201nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetProtein kinase C zeta type(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 204nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 243nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 385nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 433nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [1-999,E255K](Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 438nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 720nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 813nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.79E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase WNK2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 2.79E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 3.67E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 4.25E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 6.15E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 7.82E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 8.06E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase WNK2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 8.09E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 8.85E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 9.00E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 9.90E+3nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
