Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Nek1' and Ligand = 'BDBM139540'
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2930RVRUS Patent
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)copy SMILEScopy InChI
Affinity DataIC50: 433nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2930RVRUS Patent