Compile Data Set for Download or QSAR
Found 74 Enz. Inhib. hit(s) with all data for entry = 6981
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163627(SR-3459)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163627(SR-3459)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163623(SR-3206 | US10807944, Compound RLS2-126 | US108706...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163627(SR-3459)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163627(SR-3459)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163629(SR-3970)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163632(SR-3297 | US10807944, Compound RLS2-219 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163621(SR-3204 | US10807944, Compound RLS2-124 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163620(SR-3203 | US10807944, Compound RLS2-306 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163629(SR-3970)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163623(SR-3206 | US10807944, Compound RLS2-126 | US108706...)copy SMILEScopy InChI
Affinity DataIC50: 1.91E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163629(SR-3970)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163625(SR-3210 | US10807944, Compound RLS2-133 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163623(SR-3206 | US10807944, Compound RLS2-126 | US108706...)copy SMILEScopy InChI
Affinity DataIC50: 2.52E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 2.83E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163625(SR-3210 | US10807944, Compound RLS2-133 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 3.25E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163625(SR-3210 | US10807944, Compound RLS2-133 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 3.88E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 4.63E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163629(SR-3970)copy SMILEScopy InChI
Affinity DataIC50: 4.87E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163629(SR-3970)copy SMILEScopy InChI
Affinity DataIC50: 5.73E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 6.83E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163633(SR-3364 | US10807944, Compound RLS2-256 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 6.98E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163632(SR-3297 | US10807944, Compound RLS2-219 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163632(SR-3297 | US10807944, Compound RLS2-219 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 7.65E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163633(SR-3364 | US10807944, Compound RLS2-256 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 8.81E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163621(SR-3204 | US10807944, Compound RLS2-124 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 8.86E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163621(SR-3204 | US10807944, Compound RLS2-124 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 9.09E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 9.09E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
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