Compile Data Set for Download or QSAR
Found 107 Enz. Inhib. hit(s) with all data for entry = 7315
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189300(US9173884, BC11-8 )copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM60812(BDBM86641 | US9173884, BC11-28)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189297(US9173884, BC11-4)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86639(BC11-15 | US9173884, BC11-15)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189317(US9173884, BC11-28-7)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189315(US9173884, BC11-28-5)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189300(US9173884, BC11-8 )copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189316(US9173884, BC11-28-6)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM60808(BDBM86640 | US9173884, BC11-19)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86643(BC11-38-1 | US9173884, BC11-38-1)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189318(US9173884, BC11-28-8)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189311(US9173884, BC11-28-1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189320(US9173884, BC11-28-10)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189314(US9173884, BC11-28-4)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189297(US9173884, BC11-4)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189321(US9173884, BC11-28-11)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189319(US9173884, BC11-28-9)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189310(US9173884, BC11-19-5)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189309(US9173884, BC11-19-4)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM189307(US9173884, BC11-19-2)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86644(BC11-38-2 | US9173884, BC11-38-2)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86644(BC11-38-2 | US9173884, BC11-38-2)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86646(BC11-38-4 | US9173884, BC11-38-4)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86645(BC11-38-3 | US9173884, BC11-38-3)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform PDE2A2 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86644(BC11-38-2 | US9173884, BC11-38-2)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86646(BC11-38-4 | US9173884, BC11-38-4)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM60808(BDBM86640 | US9173884, BC11-19)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86645(BC11-38-3 | US9173884, BC11-38-3)copy SMILEScopy InChI
Affinity DataIC50: 2.13E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86644(BC11-38-2 | US9173884, BC11-38-2)copy SMILEScopy InChI
Affinity DataIC50: 2.33E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86639(BC11-15 | US9173884, BC11-15)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86639(BC11-15 | US9173884, BC11-15)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform PDE2A2 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86643(BC11-38-1 | US9173884, BC11-38-1)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86639(BC11-15 | US9173884, BC11-15)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86639(BC11-15 | US9173884, BC11-15)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM60808(BDBM86640 | US9173884, BC11-19)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86644(BC11-38-2 | US9173884, BC11-38-2)copy SMILEScopy InChI
Affinity DataIC50: 5.12E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86646(BC11-38-4 | US9173884, BC11-38-4)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86639(BC11-15 | US9173884, BC11-15)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86643(BC11-38-1 | US9173884, BC11-38-1)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform PDE2A2 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86639(BC11-15 | US9173884, BC11-15)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform PDE2A2 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86646(BC11-38-4 | US9173884, BC11-38-4)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform PDE2A2 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetIsoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1)(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Trustees of Boston College

US Patent
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0DZ6US Patent
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