Compile Data Set for Download or QSAR
Found 256 Enz. Inhib. hit(s) with all data for entry = 7336
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190202(EPZ008337 | US9175331, 32)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172176(EPZ009161 | US10155002, Compound 184 | US11052093,...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172176(EPZ009161 | US10155002, Compound 184 | US11052093,...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172176(EPZ009161 | US10155002, Compound 184 | US11052093,...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190201(EPZ008336 | US9175331, 31)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190202(EPZ008337 | US9175331, 32)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172138(EPZ007428 | US10155002, Compound 145 | US11052093,...)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190204(EPZ008491 | US9175331, 35)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190199(EPZ008286 | US9175331, 29)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190202(EPZ008337 | US9175331, 32)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172174(EPZ008681 | US10155002, Compound 182 | US11052093,...)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190183(EPZ006438 | US11052093, Compound 139 | US9175331, ...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190200(EPZ008335 | US9175331, 30)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190223(EPZ009158 | US9175331, 60)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190203(EPZ008344 | US9175331, 34)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190211(EPZ008990 | US9175331, 47)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190211(EPZ008990 | US9175331, 47)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190199(EPZ008286 | US9175331, 29)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172138(EPZ007428 | US10155002, Compound 145 | US11052093,...)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190223(EPZ009158 | US9175331, 60)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172138(EPZ007428 | US10155002, Compound 145 | US11052093,...)copy SMILES
Affinity DataIC50: 2.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190210(EPZ008989 | US9175331, 46)copy SMILES
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190198(EPZ008279 | US9175331, 27)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190183(EPZ006438 | US11052093, Compound 139 | US9175331, ...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190196(EPZ008277 | US9175331, 25)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190201(EPZ008336 | US9175331, 31)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190190(EPZ007648 | US9175331, 18)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190184(EPZ006632 | US9175331, 10)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190199(EPZ008286 | US9175331, 29)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190223(EPZ009158 | US9175331, 60)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190223(EPZ009158 | US9175331, 60)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172174(EPZ008681 | US10155002, Compound 182 | US11052093,...)copy SMILES
Affinity DataIC50: 2.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172166(EPZ008280 | US10155002, Compound 174 | US11052093,...)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190206(EPZ008494 | US9175331, 37)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190210(EPZ008989 | US9175331, 46)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172174(EPZ008681 | US10155002, Compound 182 | US11052093,...)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190204(EPZ008491 | US9175331, 35)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172166(EPZ008280 | US10155002, Compound 174 | US11052093,...)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190200(EPZ008335 | US9175331, 30)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190204(EPZ008491 | US9175331, 35)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190208(EPZ008630 | US9175331, 43)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190217(EPZ009152 | US9175331, 54)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190217(EPZ009152 | US9175331, 54)copy SMILES
Affinity DataIC50: 3nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190217(EPZ009152 | US9175331, 54)copy SMILES
Affinity DataIC50: 3.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172167(EPZ008338 | US10155002, Compound 175 | US11052093,...)copy SMILES
Affinity DataIC50: 3.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190184(EPZ006632 | US9175331, 10)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190185(EPZ007038 | US9175331, 11)copy SMILES
Affinity DataIC50: 3.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190218(EPZ009153 | US9175331, 55)copy SMILES
Affinity DataIC50: 3.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190208(EPZ008630 | US9175331, 43)copy SMILES
Affinity DataIC50: 3.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A687V](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190217(EPZ009152 | US9175331, 54)copy SMILES
Affinity DataIC50: 3.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
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