Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 4' and Ligand = 'BDBM50521156'
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Griffin Discoveries BV

Curated by ChEMBL
LigandPNGBDBM50521156(CHEMBL4452433)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR4 receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD72V6PubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Griffin Discoveries BV

Curated by ChEMBL
LigandPNGBDBM50521156(CHEMBL4452433)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of CXCL12-red from human NLuc-tagged CXCR4 receptor expressed in HEK293T cell membranes after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD72V6PubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Griffin Discoveries BV

Curated by ChEMBL
LigandPNGBDBM50521156(CHEMBL4452433)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human DEF3-fused CXCR4 receptor expressed in HEK293T cells co-expressing DAN1-HA-Galphaq/i5 assessed as inhibition of CXCL12-i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD72V6PubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Griffin Discoveries BV

Curated by ChEMBL
LigandPNGBDBM50521156(CHEMBL4452433)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at human DEF3-RLuc fused CXCR4 receptor expressed in HEK293T cells co-expressing DEF3-Beta-arrestin-2-mVenus assessed as inhibiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD72V6PubMed