Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM19857'
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Celera Genomics, Inc.

Curated by ChEMBL
LigandPNGBDBM19857(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibitory constant against rabbit cathepsin K using Z-Phe-Arg-AMC substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9GSBPubMed
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Celera Genomics, Inc.

Curated by ChEMBL
LigandPNGBDBM19857(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4N63PubMed
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Celera Genomics, Inc.

Curated by ChEMBL
LigandPNGBDBM19857(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nM EC50:  41nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4N63PubMed