Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50329850'
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Affinity against ET A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067JB
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J9672RPubMed
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against 125 I-labeled ET-1 binding to Endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2VM3
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration towards endothelin A receptor in rat.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7WD6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 24.8nMAssay Description:Displacement of [125I]ET1 from ETA receptor expressed in african green monkey CCL-81 cells monolayerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34XPPPubMed
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Compound was evaluated for the binding affinity to Endothelin A receptor in the porcine aortic smooth muscleMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M08KXPubMed