Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Geranylgeranyl pyrophosphate synthase' and Ligand = 'BDBM50013156'
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50013156(CHEMBL3262351)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP and [14C] IPP as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38XB9PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50013156(CHEMBL3262351)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B04DNPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50013156(CHEMBL3262351)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using FPP and [14C]IPP as substrate treated with enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50013156(CHEMBL3262351)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using FPP and [14C]IPP as substrate treated with enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed