Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM19293'
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19293((R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1...)copy SMILEScopy InChI
Affinity DataIC50: 15nM EC50:  64nMpH: 7.3 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7SZ4PubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19293((R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [125I-His9]ghrelin from human GHS1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HW6PubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19293((R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1...)copy SMILEScopy InChI
Affinity DataEC50:  64nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HW6PubMed