Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM50033284'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50033284(Benzyl-(2-pyridin-3-yl-quinazolin-4-yl)-amine | CH...)copy SMILEScopy InChI
Affinity DataIC50: 5.77E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50033284(Benzyl-(2-pyridin-3-yl-quinazolin-4-yl)-amine | CH...)copy SMILEScopy InChI
Affinity DataIC50: 5.77E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JH8US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50033284(Benzyl-(2-pyridin-3-yl-quinazolin-4-yl)-amine | CH...)copy SMILEScopy InChI
Affinity DataIC50: 7.08E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JH8US Patent