Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Protein cereblon' and Ligand = 'BDBM50070114'
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataKi:  8.51E+3nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence in pr...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataKi:  2.27E+4nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+3nMMore data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence in pr...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by FRET assayMore data for this Ligand-Target Pair