TargetRho-associated protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals Inc.
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant N-terminal his-tagged ROCK1 (3-543) expressed in baculovirus infected Sf9 cells using Biotin-Ahx-AKRRLSSLRA-CONH2 sub...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals Inc.
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals Inc.
Curated by ChEMBL
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
TargetRho-associated protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals Inc.
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against selected kinase ROCK1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals Inc.
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
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