Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Thyroid hormone receptor alpha' and Ligand = 'BDBM50178974'
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XJQPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Efficacy against TRAF-alpha-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed