Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Thyroid hormone receptor beta' and Ligand = 'BDBM50178974'
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 0.282nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XJQPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataEC50:  4.20nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed