Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 1132
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310899(4-[4-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310892(N-(2-methoxyethyl)-4-(6-methyl-7-oxo-1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310896(7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310895(3-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILES
Affinity DataIC50: 31nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310902(6-methyl-4-[4-(1-methyl-4-piperidyl)phenyl]-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310903(6-methyl-4-[4-[(1-methyl-4-piperidyl)methyl]phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310894(US10150767, Example 6 | tert-butyl N-[4-(6-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310901(6-cyclopropyl-4-(4-(2-hydroxypropan-2-yl)phenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310893(US10150767, Example 5 | tert-butyl 7-(6-methyl-7-o...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310897(N,N-dimethyl-3-(7-oxo-6-propyl-1H-pyrrolo[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 238nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310900(4-[4-(1-hydroxy-1-methyl-ethyl)phenyl]-6-isopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent