Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 2953
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM26303(4-aminopyrazole quinazoline, 3 | N-(2,3-difluoroph...)copy SMILEScopy InChI
Affinity DataKi:  340nM ΔG°:  -36.5kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM26304(4-aminopyrazole quinazoline, 4 | N-(2,3-difluoroph...)copy SMILEScopy InChI
Affinity DataKi:  540nM ΔG°:  -35.4kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM26306(2-{4-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM26305(4-aminopyrazole quinazoline, 5 | N-(3-fluorophenyl...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nM ΔG°:  -33.3kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM26307(4-aminopyrazole quinazoline, 7 | N-(3-fluorophenyl...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nM ΔG°:  -31.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed