Compile Data Set for Download or QSAR
Found 201 of ic50 data for complexid = 174
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM19077((5S)-5-[(1-carbamoylcyclohexyl)carbamoyl]-5-[(2S)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.0372nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Molt-4 T-cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CRSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM19081((5S)-5-[(2S)-2-{1-[4-(1H-1,3-benzodiazol-2-ylamino...)copy SMILEScopy InChI
Affinity DataIC50: 0.305nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Molt-4 T-cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CRSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17909(4-{[(2S,4S)-1-[2-(3-chloro-4-{[(2-methylphenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16885((3S)-3-{[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17910(4-{[(2S,4S)-1-[2-(3-bromo-4-{[(2-methylphenyl)carb...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17900(4-{[(2S,4S)-1-[2-(4-{[(2-chlorophenyl)carbamoyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 0.870nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17922(2-(1-{[(2S,4R)-4-(benzyloxy)-1-[2-(3-methoxy-4-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17930(2-(4-{[(2S,3S)-3-hydroxy-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16843((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9VM1PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17931(2-(4-{[(2S,4S)-4-fluoro-1-[2-(3-methoxy-4-{[(2-met...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17937(2-(4-{[(2S)-1-[2-(3-methoxy-4-{[(2-methylphenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17934(2-(4-{[(2S,4S)-4-chloro-1-[2-(3-methoxy-4-{[(2-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17924(2-(1-{[(2S,4R)-4-hydroxy-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17920(2-(1-{[(2S,4R)-4-methoxy-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17927(2-(4-{[(2S,4S)-1-[2-(3-methoxy-4-{[(2-methylphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17899(4-{[(2S,4S)-4-fluoro-1-[2-(3-methoxy-4-{[(2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17913(4-{[(2S,4S)-1-[2-(3-bromo-4-{[(2-chlorophenyl)carb...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17912(4-{[(2S,4S)-1-[2-(3-chloro-4-{[(2-chlorophenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17929(2-(4-{[(2S,3S)-3-(benzyloxy)-1-[2-(3-methoxy-4-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17916(4-{[(2S,4S)-1-[2-(3-bromo-4-{[(2-bromophenyl)carba...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17926(2-(4-{[(2S,3R,4S)-3,4-dihydroxy-1-[2-(3-methoxy-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16874((3S)-3-{[(2S,3S)-1-[(2S)-2-carbamoylpiperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16868((3S)-3-{[(2S,3S)-1-[(2S)-2-carbamoylpyrrolidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17933(2-(4-{[(2S)-4,4-difluoro-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17928(2-(4-{[(2S,4S)-1-[2-(3-methoxy-4-{[(2-methylphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17935(2-[4-({2-[2-(3-methoxy-4-{[(2-methylphenyl)carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17918(2-(4-{[(2S)-1-[2-(3-methoxy-4-{[(2-methylphenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17901(4-{[(2S,4S)-1-[2-(4-{[(2-bromophenyl)carbamoyl]ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17921(2-(4-{[(2S,4R)-4-(benzyloxy)-1-[2-(3-methoxy-4-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17925(2-(4-{[(3aR,4S,6aS)-5-[2-(3-methoxy-4-{[(2-methylp...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17915(4-{[(2S,4S)-1-[2-(4-{[(2-bromophenyl)carbamoyl]ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16892((3S)-3-{[(2S,3S)-1-[(2S)-2-carbamoylpyrrolidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17919(2-(4-{[(2S,4R)-4-methoxy-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16855((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9VM1PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17932(2-(4-{[(2S,4R)-4-fluoro-1-[2-(3-methoxy-4-{[(2-met...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17905(4-{[(2S,4S)-4-fluoro-1-[2-(3-methyl-4-{[(2-methylp...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM17936(2-(4-{[(2S)-1-[2-(3-methoxy-4-{[(2-methylphenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16893((3S)-3-{[(2S,3S)-1-[(2S)-2-carbamoylpyrrolidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16869((3S)-3-{[(2S,3S)-1-[(2R)-2-carbamoylpyrrolidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16888((3S)-3-{[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16882((3S)-3-{[(2S,3S)-1-[(2S)-2-carbamoyl-4-hydroxypyrr...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16852((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9VM1PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16894((3S)-3-{[(2S,3S)-1-[(2S)-2-carbamoylpyrrolidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16875((3S)-3-{[(2S,3S)-1-[(2R)-2-carbamoylpiperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16908((3S)-3-{[(2S,3S)-1-[(2S)-2-carbamoylpyrrolidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16870((3S)-3-{[(2S,3S)-1-[(4R)-4-carbamoyl-1,3-thiazolid...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16872((3S)-3-{[(2S,3S)-1-[(2S)-2-(carbamoylmethyl)pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16871((3S)-3-{[(2S,3S)-1-[(4S)-4-carbamoyl-1,3-thiazolid...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16878((3S)-3-{[(2S,3S)-1-[(3R)-3-carbamoyl-1,2,3,4-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of California at Davis

LigandPNGBDBM16880((3S)-3-{[(2S,3S)-1-(4-carbamoylpiperidin-1-yl)-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:Binding affinities (IC50) of the ligands were studied in a Jurkat cell adhesion assay by inhibiting the alpha-4/beta-1 mediated cell adhesion to CS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7T74PubMed
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