Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50458526'
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H] D-lysergic acid diethylamide from 5-HT7R (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by microbeta scintil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RTXPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H] D-lysergic acid diethylamide from 5-HT7R (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by microbeta scintil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RTXPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2377D11PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BPMPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BS8PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RTXPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RTXPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataEC50:  83nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RTXPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50458526(CHEMBL4205349)copy SMILEScopy InChI
Affinity DataEC50:  83nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RTXPubMed