Found 6 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM50235200' TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck& Co. Inc.
Curated by ChEMBL
Merck& Co. Inc.
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human ROMK expressed in CHO cells by electrophysiology methodMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck& Co. Inc.
Curated by ChEMBL
Merck& Co. Inc.
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck& Co. Inc.
Curated by ChEMBL
Merck& Co. Inc.
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of human ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck& Co. Inc.
Curated by ChEMBL
Merck& Co. Inc.
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck& Co. Inc.
Curated by ChEMBL
Merck& Co. Inc.
Curated by ChEMBL
Affinity DataIC50: 41.1nMAssay Description:Assay Protocol: The ROMK channel functional thallium flux assay was performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells were ...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck& Co. Inc.
Curated by ChEMBL
Merck& Co. Inc.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
