Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member A1' and Ligand = 'BDBM50009832'
TargetAldo-keto reductase family 1 member A1(Sus scrofa)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with D-glucose as substratesChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3FMZPubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity was measured against renal inner medulla aldehyde reductaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3FMZPubMed
TargetAldo-keto reductase family 1 member A1(Sus scrofa)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibitory activity was measured against pig kidney aldehyde reductase in the presence of 1 uM compound with 3-pyridine carboxaldehyde as substratesChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3FMZPubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity was measured against whole kidney aldehyde reductaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3FMZPubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with DL-glyceraldehyde as substratesChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3FMZPubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibitory activity was measured against renal outer medulla aldehyde reductaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3FMZPubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+5nMAssay Description:Inhibitory activity was measured against renal cortex aldehyde reductaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3FMZPubMed