Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Alpha-1A adrenergic receptor' and Ligand = 'BDBM50090647'
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50090647((4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxa...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Tested for binding affinity against recombinant human Alpha-1A adrenergic receptor using [125I]HEAT in competition binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K5XPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50090647((4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxa...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Binding affinity of the compound towards Alpha1A human adrenergic receptors, using [125I]-HEAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PZ582KPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50090647((4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxa...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +++:highly activeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN08GWPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50090647((4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxa...)copy SMILEScopy InChI
Affinity DataKi:  0.230nMAssay Description:Binding affinity towards Alpha1A dog adrenergic receptors, using [125I]HEAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PZ582KPubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50090647((4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxa...)copy SMILEScopy InChI
Affinity DataKi:  0.360nMAssay Description:Binding affinity towards Alpha1A rat adrenergic receptors, using [125I]HEAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PZ582KPubMed