Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Anoctamin-1' and Ligand = 'BDBM50239459'
TargetAnoctamin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50239459(CHEMBL4074929)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of ANO1 channel (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58R1TPubMed
TargetAnoctamin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50239459(CHEMBL4074929)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of [3H]norepinephrine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8P5GPubMed
TargetAnoctamin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50239459(CHEMBL4074929)copy SMILEScopy InChI
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4GK6PubMed
TargetAnoctamin-1(Mus musculus)TBA
LigandPNGBDBM50239459(CHEMBL4074929)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of GFP-fused mouse ANO1 channel expressed in HEK293A cells assessed as inhibition of ATP-induced channel current amplitude at membrane pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58R1TPubMed
TargetAnoctamin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50239459(CHEMBL4074929)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8P5GPubMed