Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Beta-lactamase TEM' and Ligand = 'BDBM178163'
TargetBeta-lactamase TEM(Escherichia coli)
NABRIVA THERAPEUTICS AG

US Patent
LigandPNGBDBM178163(US9120808, Example 41 | US9120808, Example 42)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81BT5US Patent
TargetBeta-lactamase TEM(Escherichia coli)
NABRIVA THERAPEUTICS AG

US Patent
LigandPNGBDBM178163(US9120808, Example 41 | US9120808, Example 42)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81BT5US Patent