Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2' and Ligand = 'BDBM50569929'
LigandPNGBDBM50569929(CHEMBL4876781)copy SMILES
Affinity DataKi:  38nMAssay Description:Uncompetitive inhibition of human ABCG2 transfected in human HEK293 cells assessed as Ki2 for inhibition of mitoxantrone efflux measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0M95PubMed
LigandPNGBDBM50569929(CHEMBL4876781)copy SMILES
Affinity DataKi:  42nMAssay Description:Mixed inhibition of human ABCG2 transfected in human HEK293 cells assessed as Ki2 for inhibition of mitoxantrone efflux measured after 30 mins by FAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0M95PubMed
LigandPNGBDBM50569929(CHEMBL4876781)copy SMILES
Affinity DataKi:  192nMAssay Description:Mixed inhibition of human ABCG2 transfected in human HEK293 cells assessed as Ki1 for inhibition of mitoxantrone efflux measured after 30 mins by FAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0M95PubMed
LigandPNGBDBM50569929(CHEMBL4876781)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of human ABCG2 transfected in human HEK293 cells assessed as inhibition of mitoxantrone efflux measured after 30 mins by FACS Calibur cyto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0M95PubMed