Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide 1' and Ligand = 'BDBM50356278'
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356278(CHEMBL1910947)copy SMILEScopy InChI
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in presence of 5 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356278(CHEMBL1910947)copy SMILEScopy InChI
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356278(CHEMBL1910947)copy SMILEScopy InChI
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of rat CGRPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356278(CHEMBL1910947)copy SMILEScopy InChI
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human CGRP receptor expressed in huamn HEK293 cells coexpressing CLR/RAMP1 assessed as inhibition of CGRP-stimulated cAMP production af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356278(CHEMBL1910947)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356278(CHEMBL1910947)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed