Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'Cholesteryl ester transfer protein' and Ligand = 'BDBM50094519'
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40W3VPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D7PPubMed
TargetCholesteryl ester transfer protein(Oryctolagus cuniculus)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32VSPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CETP assessed as transfer of [3H]cholesterol esters from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X0669SPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of CETP in human whole plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40W3VPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Tested for inhibiting CETP-mediated transfer of [3H]-CE from HDL to LDL in vitro under buffered assay conditions in human serum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X0669SPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of cholesteryl ester transfer protein in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D7PPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human CETP assessed as transfer of [3H]cholesterol esters from HDL to LDL in humna plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KWKPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+5nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in human serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KWKPubMed