Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B' and Ligand = 'BDBM5485'
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University of Newcastle

LigandPNGBDBM5485(6-(cyclohexylmethoxy)-9H-purin-2-amine | CHEMBL269...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nM ΔG°:  -30.8kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9MKPPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University of Newcastle

LigandPNGBDBM5485(6-(cyclohexylmethoxy)-9H-purin-2-amine | CHEMBL269...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2891424PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University of Newcastle

LigandPNGBDBM5485(6-(cyclohexylmethoxy)-9H-purin-2-amine | CHEMBL269...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0C9ZPubMed