Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50082924'
TargetDihydrofolate reductase(Pneumocystis carinii)
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50082924(6-(10,11-Dihydro-dibenzo[b,f]azepin-5-ylmethyl)-pt...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of Pneumocystis carinii DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1097PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50082924(6-(10,11-Dihydro-dibenzo[b,f]azepin-5-ylmethyl)-pt...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46R5RPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082924(6-(10,11-Dihydro-dibenzo[b,f]azepin-5-ylmethyl)-pt...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46R5RPubMed