Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase 1' and Ligand = 'BDBM35379'
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.68E+4nMAssay Description:The MKP-1 Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay has been Developed and Run at the University of Pittsbur...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2K64GGJPCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2F769WQPCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)copy SMILEScopy InChI
Affinity DataIC50: 2.42E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4VH9PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q20863PVPCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5M71PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q29G5K5DPCBioAssay