Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP' and Ligand = 'BDBM50343516'
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50343516((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Binding affinity to human XIAP linker BIR2-BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polarization-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JSDPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50343516((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)copy SMILEScopy InChI
Affinity DataKi:  64nMAssay Description:Binding affinity to His-tagged human XIAP BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization-based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JSDPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50343516((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Competitive inhibition of human XIAP linker BIR2-BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polarization-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JSDPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50343516((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)copy SMILEScopy InChI
Affinity DataIC50: 216nMAssay Description:Competitive inhibition of His-tagged human XIAP BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JSDPubMed