Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50498976'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Argenta Discovery Ltd.

Curated by ChEMBL
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins followed by addition of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataKi:  3.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataKi:  41nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataKi:  608nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataKi:  896nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of human wild type EGFR using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins followed by addition of substrate measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of EGFR phosphorylation in human NCI-H1975 cells preincubated for 1 hr followed by stimulation with EGF for 8 mins by electrochemiluminesc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50498976(CHEMBL3736183)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR phosphorylation in human NCI-H292 cells preincubated for 1 hr followed by stimulation with EGF for 8 mins by electrochemiluminesce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB