Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-beta' and Ligand = 'BDBM50003888' TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vertex Pharmaceuticals , 11010 Torreyana Road, San Diego, California 92121, United States.
Curated by ChEMBL
Vertex Pharmaceuticals , 11010 Torreyana Road, San Diego, California 92121, United States.
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of FITC-geldanamycin from recombinant HSP90beta (unknown origin) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vertex Pharmaceuticals , 11010 Torreyana Road, San Diego, California 92121, United States.
Curated by ChEMBL
Vertex Pharmaceuticals , 11010 Torreyana Road, San Diego, California 92121, United States.
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of HSP90 in HEK cells expressing full-length mHtt Q73 gene assessed as reduction of mHtt level after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
