Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Hexokinase-4' and Ligand = 'BDBM50248442'
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(...)copy SMILEScopy InChI
Affinity DataKd:  440nMAssay Description:Binding affinity to recombinant wild-type human pancreatic glucokinase expressed in Escherichia coli K-12 at 11 uM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(...)copy SMILEScopy InChI
Affinity DataEC50:  420nMAssay Description:Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(...)copy SMILEScopy InChI
Affinity DataEC50:  140nMAssay Description:Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(...)copy SMILEScopy InChI
Affinity DataEC50:  140nMAssay Description:Activation of N-terminal His-tagged human recombinant liver glucokinase expressed in Escherichia coli BL21 (DE3) by glucose-6-phosphate dehydrogenase...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(...)copy SMILEScopy InChI
Affinity DataEC50:  140nMAssay Description:Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 10 mM glucoseMore data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(...)copy SMILEScopy InChI
Affinity DataEC50:  420nMAssay Description:Activation of N-terminal His-tagged human recombinant liver glucokinase expressed in Escherichia coli BL21 (DE3) by glucose-6-phosphate dehydrogenase...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(...)copy SMILEScopy InChI
Affinity DataEC50:  420nMAssay Description:Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 2.5 mM glucoseMore data for this Ligand-Target Pair