Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50155251'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155251(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)copy SMILEScopy InChI
Affinity DataKi:  7.10nMAssay Description:In vitro binding affinity for FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38T9MPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155251(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38T9MPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155251(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+3nMAssay Description:In vitro inhibition of human platelet aggregation in suspensionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38T9MPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155251(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+3nMAssay Description:In vitro inhibition of human platelet aggregation in platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38T9MPubMed