Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'Kelch-like ECH-associated protein 1' and Ligand = 'BDBM50109398'
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataKi:  560nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataIC50: 710nMMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataIC50: 792nMAssay Description:Displacement of AF647-9-mer ETGE peptide from recombinant human biotinylated KEAP1 Kelch domain (322 to 609 residues) expressed in Escherichia coli B...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataKd:  753nMMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to KEAP1 interaction with Nrf2 (unknown origin) by SRP assayMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to Keap1 kelch domain (unknown origin) by competitive SPR assayMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50109398(CHEMBL2381968)copy SMILEScopy InChI
Affinity DataEC50:  2.60E+4nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as thermal stabiliza...More data for this Ligand-Target Pair