Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Leucyl-cystinyl aminopeptidase' and Ligand = 'BDBM50331045'
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331045((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,10-diox...)copy SMILEScopy InChI
Affinity DataKi:  94nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B60C6PubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331045((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,10-diox...)copy SMILEScopy InChI
Affinity DataKi:  633nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B60C6PubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331045((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,10-diox...)copy SMILEScopy InChI
Affinity DataKi:  5.42E+3nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in absence of 30 mM EDTA/600 uM 1,...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B60C6PubMed